Not all of the ingredients are natural:
Polyglyceryl-2 Triisostearate, Hydrogenated Polyisobutene, Polydecene, Synthetic Wax, Methyl Methacrylate Crosspolymer, Ozokerite, Trimethylolpropane Triisostearate, Cera Alba (Beeswax), C10-30 Cholesterol/Lanosterol Esters, Ethylhexyl Palmitate, Caprylic/Capric Triglyceride, Silica, Fragrance, Trihydroxystearin, Bht, Sodium Hyaluronate, Butylene Glycol, Propyl Gallate, Spilanthes Acmella Flower Extract, Caprylyl Glycol, Phenoxyethanol, Camelina Sativa Seed Oil, Benzyl Benzoate, Hexylene Glycol, Hydroxycitronellal. +/- : Aluminum Hydroxide, [+/- , Ci 15850 (Red 6 - Red 7 - Red 7 Lake), Ci 15985 (Yellow 6 Lake), Ci 19140 (Yellow 5 Lake), Ci 42090 (Blue 1 Lake), Ci 45380 (Red 21), Ci 45410 (Red 28 Lake), Ci 73360 (Red 30 - Red 30 Lake), Ci 75470 (Carmine), Ci 77491 - Ci 77492 - Ci 77499 (Iron Oxides), Ci 77891 (Titanium Dioxide), Mica].
If your lips are dry, I have read reviews that suggest maybe not because the color will pigment the dried bits and make them stand out.
To remove, I use a little cold cream (old fashion, I know, but it works). Apply a fairly generous amount and let it sit for a minute then wipe off. comes clean every time.
I recommend the lipstick, but review the ingredients list first and make sure there is nothing that will irritate your lips.
I do not find that it is difficult to get off at all(I have a hard time keeping it on). If you are sensitive, be aware that this lipstick has fragrance.
Not sure about how natural they are but this lipstick is amazing. I have super sensitive skin and I love this formula. It stays on for a few hours and doesn't irritate my lips at all (no dryness). The smell is great too (not overpowering). Also, try their 0 flaw foundation (it is truly perfect for sensitive/combination skin).