The instructions are not much more informative than what Sephora has posted under "How to Use," which is surprising for a pricey product. The notable difference is that the box/insert also instructs to "gently massage, using circular motions, to buff away dead skin cells" after applying the copper paste for Step One, and to use a lukewarm damp cloth in the removal. A peel requires 1/3-1/2 of each tube. I use 1/3 of each per peel for my face and don't feel like I'm applying it sparingly. If I were to also use it on my neck as the instructions suggests, I would need 1/2 of each tube per peel. So, the box will last between 16-24 applications, but I think it's safe to say it'll give at least 16 applications for most (90%) people. How long the whole package lasts depends on if you get closer to 16 applications or 24 applications, and how often you use it. How often you should/could use it is not listed anywhere on the box or the insert, but the Sephora description says "For use once or twice weekly only," and I think that's a reasonable frequency. Another thing: before I bought it, I read all the reviews and there were many who complained that there's too much product per tube and that they're not resealable so it's a waste. That is not true--these tubes ARE resealable. Apparently the tubes used to have a screw cap, but now they come with a twist-off. Well, after you twist off the top and dispense the product, you just flip the top over and plug the open tube with the tip, which clicks into place. I'm surprised so many people couldn't figure this out! Hope that helps.