Having used Differin, Retin-A Micro, several others, this is a great choice is you have moderate acne, as the retinol in it is very concentrated (strong) at 2%, while most OTC products you'll find are, at their strongest, 1%. While Rx creams and gels will be stronger, what you should be aware of is their harshness if you have sensitive skin. You'll have peely, scaly skin for a month or two getting adjusted to the rigorous regimen of the drug, whereas Brandt's formula has an ingredient called Oliveactive that actually prevents this effect.
compared to retin-a this is much less harsh, no redness or itching, but not sure if it works as great for wrinkles or acne yet. What I do like is every moring I'm not peeling or red, but my face seems less plump and wrinkle free a bit...will comment again in a few weeks