That depends on how dry your skin is to start with and how much you're applying this product. I have combo/oily skin and I applied this product twice daily to smaller spots on my face. I used an intensive moisturizer at night, and it seemed to keep the dryness at bay. Start by using this once daily with your regular moisturizer and see how your skin responds, then you can adjust.

You don't need too much... a very thin layer or it will dry out your skin. If it does dry out your skin, try doing it just at night before bed instead of in the morning AND at night.

It has not dried my face out at all, I use it every morning before I put anything else on my face.

Compared to the 2.5% Benzoyl Peroxide I was using, this is far less drying, even though it is 5%! My skin really dried and flaked with the other Benzoyl Peroxide I was using, but with this, it makes my skin a bit drier but not to the point of flaking, just enough to mattify and tighten a bit.

It certainly can be drying. I have combination skin, more prone to be oily in the summertime. I use this product twice a day, but am sure to moisturize each time I do with an oil-free moisturizer, else I get aligator-like...not pretty!

After getting a facial and consultation with the Kate Somerville experts from their flagship store in LA, I was recommended to actually use the Anti Bac in addition to the Goats milk lotion. The Anti Bac will help clear and prevent acne, while the Goats milk lotion promotes healing of my existing acne blemishes and scars for my combination skin. Hope this is helpful!

This product is compatible with any moisturizing cream that does not contain retinoids, salicylic acid, other alpha/beta hydroxy acids, and the like. I too have sensitive skin and follow this lotion with the Goat Milk cream, which has been a great combination for me. As with most intensive treatments, it would be best to apply this lotion on a clean face at night, rather than during the day, if only applying once daily. Remember that the chemical exfoliation will increase the skin's sensitivity to UV rays, so be vigilant about using some form of sunscreen or sunscreen-containing product of at least SPF 15 during the day.

I also have pretty sensitive skin and only use this once a day. I haven't been sticking to a super strict routine or anything, if I use it in the morning I don't use it at night, etc. I don't know about the goat's milk, but definitely use a moisturizer with this!

I would recommend using this at night as it is quite drying so it may make you uncomfortable during the day.

If you're only going to apply this once, I would choose night. I think the product will work better when applied directly to your skin without any of the other barriers that you'd get during the day, i.e., makeup, powder, primers, excess oil, etc.

It is a moisterizer, so, in theory, you shouldn't need another one. It can be drying though. When I first tried it, I was given a sample, and the lady told me to only use it once a day, so it didn't dry me out too much. I wash my face in the mornings and apply Clinique's Dramatically different gel, and at night I wash my face and apply this. If you have really dry skin, to where you would need an extra moisterizer, this product might not be a good idea, because it can be drying. When I use it, only applying this at night, it makes my skin feel moisterized, and really silky and smooth.

yes, just make sure the clearing lotion has completely dried. i find this product to be very drying, so i have always put a thicker lotion on over the top and wake up with clear and soft skin!

It probably is. I had this same problem (I returned it tho) and I would see how the lotion would begin to move around the anti-bac lotion in white streaks. try maybe the lotion first, then the anti bac.

You definitely need a moiturizer on top of it. Be careful and gentle with how you apply the clearing lotion. Do NOT rub it in. Just tap on gently. Then follow with a calming moiturizer, preferrably a cream. I use Perricone nourishing moisturizer for senstive skin and the combo has been working great for me. Perricone instantly reduced the uncomfortable itchy and tingeling feeling Also it does a wonderful moiturizing job!

Anti Bac is more of a treatment, I would highly recommend using a moisturizer over it. One of Kate's tips is to mix it with her Goat Milk cream to calm and soften skin. I personally use it with Oil Free if I do use it during the day and a high SPF, if I use it at night I use Deep Tissue.

I use this twice daily -- once at night after removing my makeup, and again in the morning, under my makeup. If you have sensitive skin, I would just use this at night.

I use this in the morning before serum and moisturizer and at night the same way.

Twice a day, morning and night.

I use the Anti-Bac clearing lotion (about one pump is good) both morning and night. Definitely follow up with a moisturizer!

If you only get the occasional pimple, I would go for Kate Somerville's Sulfur Spot Treatment. I used it for about a year and it works great! The only reason I switched to this product was because my skin sort of became used to the spot treatment and it stopped working as well.

I don't know about just putting this on pimples, if that is all you need I would use Eradikate, which dries them really fast. I use this to prevent pimples and for that it is a miracle product. Hope that helps!

Yes! A lot more gentle and works pretty effectively overnight on pimples.

my skin is senstive as well, plus I don't get the small pimples my are the cyst type and it really has worked, nothing else has done what this product has done!!

Definitely use a moisturizer after. I use the Anti Bac, then an Oil Free moisturizer, then my face primer, foundation and powder and I have no problems with it under my moisturizer or makeup.

I apply my moisturizer under the Antibac and again on top, if needed. I typically get very dry and irritated from benzoyl peroxide products, so if this is the case for you, then you need to lessen the amount and/or times of day you're applying. I find once before bed works enough to get it going and maybe only 2-3 days worth otherwise you're just damage skin and the pimple has already gotten the clue that you're trying to dry it out. Actual benzoyl peroxide in the bottle that you use for cuts and scrapes works just as well and cheaper, but you have to be careful because it will dry out skin MUCH quicker.

I always use the clearing lotion; wait 5-10 minutes to ensure the product has absorbed well into my skin (it only take a minute or so to dry but I like to wait anyway); then apply my moisturizer and then make up. This works really well for me. I am able to use it twice a day with zero dryness and irritation and it is keeping my skin clear.

I, too also used a 10% benzoyl peroxide cream, which did not seem to do much, but for some reason, this works a ton better and is less drying. It prevents pimples, where the other I used just helped dry up and didn't seem to prevent.

Drug store benzoyl peroxide tends to REALLY dry out my skin. I can put this all over my face twice a day, and have no problems with weird flaking. I used 2.5% Benzoyl Peroxide from CVS, and now that I've used this, I will never go back.

If it does anything better than the drug store versions, whether more or less percentage of benzoyl peroxide, this one didn't irritate or dry out my skin as quickly, but worked equally as well.

I use two pumps at night and one pump during the day religiously, and my it lasted four months.

the first answer was way off topic.
It should last you anwhere from 3-4 months depending on how heavy you apply it. it could last you 5 months even 6 id imagine. because i just use a little tad to apply over my face - really light coat with main application on cheeks and chin. then use a moisturizer - dont rely on this as your moisturizer. even if you have oily skin id use a moisturizer because it wil help prevent any damage from free radicals and uva rays (if it has spf in it) which youll need because this is an acne med

I don't think anyone can answer this as it depends on how you're using it. I only use this once a day, if needed. Sometimes I use 2 pumps worth on my face, back and chest, and some days I use half a pump on a few spot on my face. I've had mine for a couple months now and have a lot left.

I only use this at night and it doesn't dry my face out at all. You should find a different lotion that just moisturizes your skin throughout the day and as long as your wash your face every night you should be ok

I like Nourish (with a drop of Quench Serum in the winter) in the morning and Cytocell at night. I sometimes use a drop of Argan oil at night over the Cytocell if I am more dry. Works great!

I really recommend adding the REN ClearCalm3 Night Serum with this product. I have been using that at night and really believe that it is helping me to avoid any dryness that can happen with the Anti-Bac Lotion. I haven't had one flakey patch of skin or irritation and I think it's because the night serum is so gently and hydrating. The REN serum also helps to fade past acne marks which is terrific!

I would apply it only on the areas where you typically breakout. It also prevents breakouts too, not just treats it. But if you only breakout on the lower half of your face, I would just use it on those areas.

I only apply it to the affected areas. I think this is best if you have sensitive skin like me so that you don't irritate areas of your face that don't need it.